Overview
In this trial, investigators are testing whether or not green light exposure can help reduce epileptic spikes for people with medically-refractory epilepsy. The study will test how safe, tolerable, and effective this treatment is for people with epilepsy.
Study Information
In this study, 16 participants will undergo 120 minutes of a narrow band of green light (520-540 nm) at low intensities that are known to be tolerable for adults and children. Participants will undergo a 30 minute scalp EEG test before and after the exposure to monitor spike frequency and see if there is a change in epileptic spikes per minute.
Inclusion Criteria
- Ages 6 months-30 years
- Epileptic spike frequency ≥1 epileptic spike per minute at baseline, as determined by scalp EEG recording
- Admitted to the Boston Children’s Hospital Epilepsy Long Term Monitoring Unit at the time of enrollment
Exclusion Criteria
- Cataracts
- Retinol disease
- Any history of or currently not well controlled ophthalmic disease that prevents transmission from the retina to the optic nerve
- Clinical seizure 4 hours or less before anticipated green light exposure
Location
Boston Children’s Hospital
Boston, Massachusetts, United States, 02130
Contact: Harper L Kaye 617-355-4875 neuromodulation@childrens.harvard.edu
Principal Investigator: Alexander Rotenberg, MD, Ph D
Principal Investigator: Phillip Pearl, MD
Sub-Investigator: Harper L Kaye
Sponsors/Collaborators
Boston Children’s Hospital
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